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Seasonality of Vitamin D Insufficiency in Children of Moscow

Received: 11 July 2017     Accepted: 23 October 2017     Published: 30 November 2017
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Abstract

The article presents the analysis of vitamin D levels in children of various age groups residing in Moscow and assesses the seasonality of vitamin D variations in this population group. In this work, the results of 25 (ОН) D level measurement in 1041 children in the age from 1 month to 18 years collected in the period since 2012 to 2015 have been analyzed. In accordance with the analysis, in spite of the age, the high percentage of vitamin D insufficiency was detected among children in Moscow. The generally accepted optimum level of vitamin D metabolite – calcidiol in blood (>30 ng/ml) was observed only in the small part of the study participants (26%), while the larger part (74%) had the insufficient level of vitamin D of various intensity: 28% - insufficiency (20-29 ng/ml), 33% - deficiency (<20 ng/ml), 13% - severe deficiency (<10 ng/ml). With the age, the insufficiency level was more pronounced. The seasonality analysis showed the significant difference of vitamin D level between summer and winter seasons (p=0.01). The greatest decrease of vitamin D levels was observed in winter (median level of 25(ОН)D 17.0 (11.0; 25.0) ng/ml). In summer months, the relative calcidiol gain was fixed (median – 22.9 (18.0; 33.0) ng/ml) which, however, did not achieve the normal level. Children and, in particular, adolescents residing in Moscow need year-round hypovitaminosis D prophylaxis with cholecalciferol products.

Published in American Journal of Pediatrics (Volume 3, Issue 6)
DOI 10.11648/j.ajp.20170306.14
Page(s) 83-88
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Vitamin D, Cholecalciferol, Hypovitaminosis D, Vitamin D Deficiency, Seasonal Variations of Vitamin D

References
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    Zakharova Irina, Borovik Tatyana, Pludowski Pawel, Tvorogova Tatyana, Solovyeva Ekaterina, et al. (2017). Seasonality of Vitamin D Insufficiency in Children of Moscow. American Journal of Pediatrics, 3(6), 83-88. https://doi.org/10.11648/j.ajp.20170306.14

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    ACS Style

    Zakharova Irina; Borovik Tatyana; Pludowski Pawel; Tvorogova Tatyana; Solovyeva Ekaterina, et al. Seasonality of Vitamin D Insufficiency in Children of Moscow. Am. J. Pediatr. 2017, 3(6), 83-88. doi: 10.11648/j.ajp.20170306.14

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    AMA Style

    Zakharova Irina, Borovik Tatyana, Pludowski Pawel, Tvorogova Tatyana, Solovyeva Ekaterina, et al. Seasonality of Vitamin D Insufficiency in Children of Moscow. Am J Pediatr. 2017;3(6):83-88. doi: 10.11648/j.ajp.20170306.14

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  • @article{10.11648/j.ajp.20170306.14,
      author = {Zakharova Irina and Borovik Tatyana and Pludowski Pawel and Tvorogova Tatyana and Solovyeva Ekaterina and Sugyan Narine and Antonenko Natalia and Balashova Nadejda and Kuular Nadejda and Marchenko Vera and Perova Svetlana and Prostakova Valentina and Simakova Natalia and Simonenko Irina and Vasilyeva Svetlana and Mozzhukhina Maria and Koroleva Ekaterina and Rakhteenko Alina and Dmitrieva Yulia and Klimov Leonid and Kuryaninova Victoria},
      title = {Seasonality of Vitamin D Insufficiency in Children of Moscow},
      journal = {American Journal of Pediatrics},
      volume = {3},
      number = {6},
      pages = {83-88},
      doi = {10.11648/j.ajp.20170306.14},
      url = {https://doi.org/10.11648/j.ajp.20170306.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20170306.14},
      abstract = {The article presents the analysis of vitamin D levels in children of various age groups residing in Moscow and assesses the seasonality of vitamin D variations in this population group. In this work, the results of 25 (ОН) D level measurement in 1041 children in the age from 1 month to 18 years collected in the period since 2012 to 2015 have been analyzed. In accordance with the analysis, in spite of the age, the high percentage of vitamin D insufficiency was detected among children in Moscow. The generally accepted optimum level of vitamin D metabolite – calcidiol in blood (>30 ng/ml) was observed only in the small part of the study participants (26%), while the larger part (74%) had the insufficient level of vitamin D of various intensity: 28% - insufficiency (20-29 ng/ml), 33% - deficiency (<20 ng/ml), 13% - severe deficiency (<10 ng/ml). With the age, the insufficiency level was more pronounced. The seasonality analysis showed the significant difference of vitamin D level between summer and winter seasons (p=0.01). The greatest decrease of vitamin D levels was observed in winter (median level of 25(ОН)D 17.0 (11.0; 25.0) ng/ml). In summer months, the relative calcidiol gain was fixed (median – 22.9 (18.0; 33.0) ng/ml) which, however, did not achieve the normal level. Children and, in particular, adolescents residing in Moscow need year-round hypovitaminosis D prophylaxis with cholecalciferol products.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Seasonality of Vitamin D Insufficiency in Children of Moscow
    AU  - Zakharova Irina
    AU  - Borovik Tatyana
    AU  - Pludowski Pawel
    AU  - Tvorogova Tatyana
    AU  - Solovyeva Ekaterina
    AU  - Sugyan Narine
    AU  - Antonenko Natalia
    AU  - Balashova Nadejda
    AU  - Kuular Nadejda
    AU  - Marchenko Vera
    AU  - Perova Svetlana
    AU  - Prostakova Valentina
    AU  - Simakova Natalia
    AU  - Simonenko Irina
    AU  - Vasilyeva Svetlana
    AU  - Mozzhukhina Maria
    AU  - Koroleva Ekaterina
    AU  - Rakhteenko Alina
    AU  - Dmitrieva Yulia
    AU  - Klimov Leonid
    AU  - Kuryaninova Victoria
    Y1  - 2017/11/30
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ajp.20170306.14
    DO  - 10.11648/j.ajp.20170306.14
    T2  - American Journal of Pediatrics
    JF  - American Journal of Pediatrics
    JO  - American Journal of Pediatrics
    SP  - 83
    EP  - 88
    PB  - Science Publishing Group
    SN  - 2472-0909
    UR  - https://doi.org/10.11648/j.ajp.20170306.14
    AB  - The article presents the analysis of vitamin D levels in children of various age groups residing in Moscow and assesses the seasonality of vitamin D variations in this population group. In this work, the results of 25 (ОН) D level measurement in 1041 children in the age from 1 month to 18 years collected in the period since 2012 to 2015 have been analyzed. In accordance with the analysis, in spite of the age, the high percentage of vitamin D insufficiency was detected among children in Moscow. The generally accepted optimum level of vitamin D metabolite – calcidiol in blood (>30 ng/ml) was observed only in the small part of the study participants (26%), while the larger part (74%) had the insufficient level of vitamin D of various intensity: 28% - insufficiency (20-29 ng/ml), 33% - deficiency (<20 ng/ml), 13% - severe deficiency (<10 ng/ml). With the age, the insufficiency level was more pronounced. The seasonality analysis showed the significant difference of vitamin D level between summer and winter seasons (p=0.01). The greatest decrease of vitamin D levels was observed in winter (median level of 25(ОН)D 17.0 (11.0; 25.0) ng/ml). In summer months, the relative calcidiol gain was fixed (median – 22.9 (18.0; 33.0) ng/ml) which, however, did not achieve the normal level. Children and, in particular, adolescents residing in Moscow need year-round hypovitaminosis D prophylaxis with cholecalciferol products.
    VL  - 3
    IS  - 6
    ER  - 

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Author Information
  • Department of Pediatric, FSBEI HPT “Russian Medical Academy of Postgraduate Continuing Education” of the Ministry of Health, Moscow, Russia Federation

  • Department of Nutrition Children, FSAI ?National Scientific and Practical Center of Children’s Health? of the Ministry of Health, Moscow, Russia Federation

  • Department of Biochemistry and of Experimental Medicine, The Children’s Memorial Health Institute, Warsaw, Poland

  • Department of Pediatric, FSBEI HPT “Russian Medical Academy of Postgraduate Continuing Education” of the Ministry of Health, Moscow, Russia Federation

  • Department of Pediatric, FSBEI HPT “Russian Medical Academy of Postgraduate Continuing Education” of the Ministry of Health, Moscow, Russia Federation

  • Department of Pediatric, FSBEI HPT “Russian Medical Academy of Postgraduate Continuing Education” of the Ministry of Health, Moscow, Russia Federation

  • Department of Pediatric, FSBI “Pediatric Medical Center” of the Presidential Administration of the Russian Federation, Moscow, Russia Federation

  • Department of Pediatric, FSBI “Pediatric Medical Center” of the Presidential Administration of the Russian Federation, Moscow, Russia Federation

  • Department of Pediatric, FSBI “Pediatric Medical Center” of the Presidential Administration of the Russian Federation, Moscow, Russia Federation

  • Department of Pediatric, FSBI “Pediatric Medical Center” of the Presidential Administration of the Russian Federation, Moscow, Russia Federation

  • Department of Pediatric, FSBI “Pediatric Medical Center” of the Presidential Administration of the Russian Federation, Moscow, Russia Federation

  • Department of Pediatric, FSBI “Pediatric Medical Center” of the Presidential Administration of the Russian Federation, Moscow, Russia Federation

  • Department of Pediatric, FSBI “Pediatric Medical Center” of the Presidential Administration of the Russian Federation, Moscow, Russia Federation

  • Department of Pediatric, FSBI “Pediatric Medical Center” of the Presidential Administration of the Russian Federation, Moscow, Russia Federation

  • Department of Pediatric, FSBEI HPT “Russian Medical Academy of Postgraduate Continuing Education” of the Ministry of Health, Moscow, Russia Federation

  • Department of Pediatric, FSBEI HPT “Russian Medical Academy of Postgraduate Continuing Education” of the Ministry of Health, Moscow, Russia Federation

  • Department of Pediatric, Clinic of Group of Companies “Mother and a Child”, Moscow, Russia Federation

  • Department of Pediatric, FSBEI HPT “Russian Medical Academy of Postgraduate Continuing Education” of the Ministry of Health, Moscow, Russia Federation

  • Department of Pediatric, FSBEI HPT “Russian Medical Academy of Postgraduate Continuing Education” of the Ministry of Health, Moscow, Russia Federation

  • Department of Pediatric, FSBEI HE “Stavropol State Medical University” of the Ministry of Health, Stavropol, Russia Federation

  • Department of Pediatric, FSBEI HE “Stavropol State Medical University” of the Ministry of Health, Stavropol, Russia Federation

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