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Dengue Infection in Children: Clinical Profile and Outcome in Dhaka City

Received: 21 June 2019     Accepted: 15 July 2019     Published: 31 July 2019
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Abstract

Dengue is a self-limiting acute mosquito born disease caused by Dengue virus. Dengue infections may be asymptomatic or can result in a wide spectrum of disease severity ranging from an influenza-like illness (Dengue fever) to the life-threatening Dengue hemorrhagic fever (DHF)/Dengue shock syndrome (DSS). We aimed to analyze the variation in clinical spectrum, outcome and possible risk factors for fatality among Dengue infected children. This was an observational study carried out over a period of one year involving 89 children up to 15 years of age. Upon clinical suspicion Dengue was confirmed by NS 1 antigen and/or Dengue antibody IgM, IgG. Positive Dengue cases were enrolled & interviewed and the information obtained related to the risk factors, clinical presentation, pattern of Dengue infection and outcome were documented in the pre-structured questionnaire. Among the 89 studied children the highest percentage (51.68%) was between 0-5 year and male female ratio was 1.2: 1. Mosquito net was not used by (74.15%) children and there was source of stagnant water in/near the house of (13.48%) children. Fever was present in (100%), rash in (48.31%), nausea/vomiting in (37.07%), headache in (12.35%), myalgia/arthralgia/backache (13.48%), retro orbital pain (1.12%) and abdominal pain in (23.59%) patient. Epistaxis was the commonest (70%) form of bleeding. CNS involvement was in the form of restlessness/irritability (19.10%), altered sensorium (2.24%) and convulsion. Pleural effusion was commoner than ascites; (25.84%) and (12.35%) respectively. Among the enrolled children Dengue fever was (74.15%), Dengue hemorrhagic fever (6.74%) and Dengue shock syndrome (19.10%). Two patients died out of 17 from Dengue shock syndrome which was (11.76%). World Health Organization (WHO) guideline based management should be applied in assessing and managing Dengue cases to reduce mortality rate. Public awareness should be widened to prevent Dengue.

Published in American Journal of Pediatrics (Volume 5, Issue 3)
DOI 10.11648/j.ajp.20190503.16
Page(s) 111-115
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Dengue, Infection, Hemorrhage, Shock

References
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Cite This Article
  • APA Style

    Kamrunnaher Shultana, A. Z. M. Motiur Rahman, Abdullah Al Baki, Md. Shohidul Islam Khan, Bishwajit Deb, et al. (2019). Dengue Infection in Children: Clinical Profile and Outcome in Dhaka City. American Journal of Pediatrics, 5(3), 111-115. https://doi.org/10.11648/j.ajp.20190503.16

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    ACS Style

    Kamrunnaher Shultana; A. Z. M. Motiur Rahman; Abdullah Al Baki; Md. Shohidul Islam Khan; Bishwajit Deb, et al. Dengue Infection in Children: Clinical Profile and Outcome in Dhaka City. Am. J. Pediatr. 2019, 5(3), 111-115. doi: 10.11648/j.ajp.20190503.16

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    AMA Style

    Kamrunnaher Shultana, A. Z. M. Motiur Rahman, Abdullah Al Baki, Md. Shohidul Islam Khan, Bishwajit Deb, et al. Dengue Infection in Children: Clinical Profile and Outcome in Dhaka City. Am J Pediatr. 2019;5(3):111-115. doi: 10.11648/j.ajp.20190503.16

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  • @article{10.11648/j.ajp.20190503.16,
      author = {Kamrunnaher Shultana and A. Z. M. Motiur Rahman and Abdullah Al Baki and Md. Shohidul Islam Khan and Bishwajit Deb and Dhiman Chowdhury and A. B. M. Rezaul Karim Mir and Fariha Sabrina and Shadia Zaman and Md. Mozammel Haque},
      title = {Dengue Infection in Children: Clinical Profile and Outcome in Dhaka City},
      journal = {American Journal of Pediatrics},
      volume = {5},
      number = {3},
      pages = {111-115},
      doi = {10.11648/j.ajp.20190503.16},
      url = {https://doi.org/10.11648/j.ajp.20190503.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20190503.16},
      abstract = {Dengue is a self-limiting acute mosquito born disease caused by Dengue virus. Dengue infections may be asymptomatic or can result in a wide spectrum of disease severity ranging from an influenza-like illness (Dengue fever) to the life-threatening Dengue hemorrhagic fever (DHF)/Dengue shock syndrome (DSS). We aimed to analyze the variation in clinical spectrum, outcome and possible risk factors for fatality among Dengue infected children. This was an observational study carried out over a period of one year involving 89 children up to 15 years of age. Upon clinical suspicion Dengue was confirmed by NS 1 antigen and/or Dengue antibody IgM, IgG. Positive Dengue cases were enrolled & interviewed and the information obtained related to the risk factors, clinical presentation, pattern of Dengue infection and outcome were documented in the pre-structured questionnaire. Among the 89 studied children the highest percentage (51.68%) was between 0-5 year and male female ratio was 1.2: 1. Mosquito net was not used by (74.15%) children and there was source of stagnant water in/near the house of (13.48%) children. Fever was present in (100%), rash in (48.31%), nausea/vomiting in (37.07%), headache in (12.35%), myalgia/arthralgia/backache (13.48%), retro orbital pain (1.12%) and abdominal pain in (23.59%) patient. Epistaxis was the commonest (70%) form of bleeding. CNS involvement was in the form of restlessness/irritability (19.10%), altered sensorium (2.24%) and convulsion. Pleural effusion was commoner than ascites; (25.84%) and (12.35%) respectively. Among the enrolled children Dengue fever was (74.15%), Dengue hemorrhagic fever (6.74%) and Dengue shock syndrome (19.10%). Two patients died out of 17 from Dengue shock syndrome which was (11.76%). World Health Organization (WHO) guideline based management should be applied in assessing and managing Dengue cases to reduce mortality rate. Public awareness should be widened to prevent Dengue.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Dengue Infection in Children: Clinical Profile and Outcome in Dhaka City
    AU  - Kamrunnaher Shultana
    AU  - A. Z. M. Motiur Rahman
    AU  - Abdullah Al Baki
    AU  - Md. Shohidul Islam Khan
    AU  - Bishwajit Deb
    AU  - Dhiman Chowdhury
    AU  - A. B. M. Rezaul Karim Mir
    AU  - Fariha Sabrina
    AU  - Shadia Zaman
    AU  - Md. Mozammel Haque
    Y1  - 2019/07/31
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ajp.20190503.16
    DO  - 10.11648/j.ajp.20190503.16
    T2  - American Journal of Pediatrics
    JF  - American Journal of Pediatrics
    JO  - American Journal of Pediatrics
    SP  - 111
    EP  - 115
    PB  - Science Publishing Group
    SN  - 2472-0909
    UR  - https://doi.org/10.11648/j.ajp.20190503.16
    AB  - Dengue is a self-limiting acute mosquito born disease caused by Dengue virus. Dengue infections may be asymptomatic or can result in a wide spectrum of disease severity ranging from an influenza-like illness (Dengue fever) to the life-threatening Dengue hemorrhagic fever (DHF)/Dengue shock syndrome (DSS). We aimed to analyze the variation in clinical spectrum, outcome and possible risk factors for fatality among Dengue infected children. This was an observational study carried out over a period of one year involving 89 children up to 15 years of age. Upon clinical suspicion Dengue was confirmed by NS 1 antigen and/or Dengue antibody IgM, IgG. Positive Dengue cases were enrolled & interviewed and the information obtained related to the risk factors, clinical presentation, pattern of Dengue infection and outcome were documented in the pre-structured questionnaire. Among the 89 studied children the highest percentage (51.68%) was between 0-5 year and male female ratio was 1.2: 1. Mosquito net was not used by (74.15%) children and there was source of stagnant water in/near the house of (13.48%) children. Fever was present in (100%), rash in (48.31%), nausea/vomiting in (37.07%), headache in (12.35%), myalgia/arthralgia/backache (13.48%), retro orbital pain (1.12%) and abdominal pain in (23.59%) patient. Epistaxis was the commonest (70%) form of bleeding. CNS involvement was in the form of restlessness/irritability (19.10%), altered sensorium (2.24%) and convulsion. Pleural effusion was commoner than ascites; (25.84%) and (12.35%) respectively. Among the enrolled children Dengue fever was (74.15%), Dengue hemorrhagic fever (6.74%) and Dengue shock syndrome (19.10%). Two patients died out of 17 from Dengue shock syndrome which was (11.76%). World Health Organization (WHO) guideline based management should be applied in assessing and managing Dengue cases to reduce mortality rate. Public awareness should be widened to prevent Dengue.
    VL  - 5
    IS  - 3
    ER  - 

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Author Information
  • Department of Pediatrics and PICU, Square Hospitals Ltd., Dhaka, Bangladesh

  • Department of Pediatrics, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Pediatrics, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Pediatrics, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Pediatrics, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Pediatrics, Chattogram Medical College Hospital, Chattogram, Bangladesh

  • Department of Medicine, 250 Bedded Hospital, Moulvibazar, Bangladesh

  • Department of Pediatrics and PICU, Square Hospitals Ltd., Dhaka, Bangladesh

  • Department of Pediatrics and PICU, Square Hospitals Ltd., Dhaka, Bangladesh

  • Department of Pediatrics, 250 Bedded Hospital, Moulvibazar, Bangladesh

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